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T1-T2 DUAL MODAL MRI CONTRAST AGENTS
专利权人:
发明人:
Jin Woo CHEON,Jin-Sil CHOI
申请号:
US14336827
公开号:
US20140328765A1
申请日:
2014.07.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates a T1-T2 dual-modal MRI (magnetic resonance imaging) contrast agent, comprising (a) a first layer consisting of T1 contrast material (b) a second layer consisting of T2 contrast material and (c) a separating layer which is present in a space between the first layer and the second layer, and inhibits a reciprocal interference between T1 contrast material and T2 contrast material, and a heat-generating composition and a drug delivery composition having the same. The T1-T2 dual-modal contrast agent of the present invention may generate both T1 and T2 signal and thus observe the signal complementarily, resulting in accurate diagnosis through reduction of misdiagnosis. Further, T1 and T2 MR imaging may be simultaneously obtained by simple operation within the same MR imaging device, enabling to remarkably reduce a diagnosis time and diagnosis cost. In addition, the particle constituting the T1-T2 dual-modal contrast agent of the present invention may be applied to hyperthermia and drug delivery systems.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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