The present invention relates to a prosthetic heart valve system (10; 200; 300) and a delivery system (400) therefor, the prosthetic heart valve system (10; 200; 300) comprising a heart valve element (20) with expandable generally tubular stent support (102) forming a wire frame, wherein the tubular stent support (102) comprises a plurality of adjacent rows of interconnected, substantially diamond-shaped cell structures (171) extending, along and in parallel to the longitudinal direction, between the proximal end (103) and distal end (107), and wherein the stent support (102), in a medial portion (105), comprises a circumferential row (170) of a plurality of wire anchor structures (171) which wire anchor structures (171) are spaced from one another and attached to the wire frame and which, in respect to the longitudinal axis (131) of the stent support (102), at least partially protrude outward at an angle α. The prosthetic heart valve system (10; 200; 300) may also comprise a stent(graft)-element (310).