Gwangju Institute of Science and Technology;Korea Advanced Institute of Science and Technology;Kyungpook National University Industry-Academic Cooperation Foundation;CURACLE Co., Ltd.
发明人:
AHN, Jin Hee,KIM, Hail,SUH, Jaemyoung,LEE, In-Kyu,KIM, Kwang-eun,PARK, Kun-Young,BAE, Eun Jung,SHONG, Ko Eun,PAGIRE, Suvarna Haus-Habhau,LIM, Ajin,JEON, Jae-Han,PAGIRE, Haushabhau Shivaji,ZHANG, Haiyi
申请号：
EP18848270
公开号：
EP3674303A1
申请日:
2018.08.24
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention relates to a novel tryptophan hydroxylase inhibitor and a pharmaceutical composition including same, wherein the novel tryptophan hydroxylase inhibitor has an excellent inhibitory effect on TPH1, and thus can be usefully used for the prevention or treatment of disorders, such as metabolic disorders, cancer, digestive or cardiovascular system disorders, related to TPH1 activity. In particular, the novel tryptophan hydroxylase inhibitor has an excellent treatment effect on inflammatory bowel disorders, and thus can be usefully used for the treatment of inflammatory bowel disorder.
