Swati P. Mercer,Anthony J. Roecker,Theresa Williams,Xu-Fang Zhang
申请号：
US13265672
公开号：
US20120040998A1
申请日:
2010.04.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to 2-alkylpiperidines which are positive allosteric modulators of metabotropic glutamate receptors, particularly the mGluR5 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
