Gregory Alan Stoloff,Wilson Romero Caparros-Wanderley
申请号:
US13906232
公开号:
US20130243804A1
申请日:
2013.05.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope:SEQ ID 1DLEALMEWLKTRPILSPLTKGILGFVFTLTVPSEQ ID 2LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHSSEQ ID 3DLIFLARSALILRGSVAHKSCSEQ ID 4PGIADIEDLTLLARSMVVVRPSEQ ID 5LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQSEQ ID 6IIGILHLILWILDRLFFKCIYRLFwherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.