Tarlochan S. Nijjar;Philip W. Payne;Robin Barbour;Dale B. Schenk
发明人:
Dale B. Schenk,Tarlochan S. Nijjar,Philip W. Payne,Robin Barbour
申请号:
US13368260
公开号:
US20120204275A1
申请日:
2012.02.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides antibodies that preferentially bind to an ApoE(1-272) fragment relative to ApoE(1-299). These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of neurological diseases.