The present description relates to the use of polycyclic 2-pyridinone compounds and forms thereof for treating or ameliorating Neisseria gonorrhoeae. The present description relates to use of substituted polycyclic compounds for treating or ameliorating Neisseria gonorrhoeae (N. gonorrhoeae) in a subject in need thereof comprising, administering an effective amount of the compound to the subject, wherein the compound is selected from a compound of Formula (I) or Formula (II): wherein R1, R2, R4, R5, R6, R7, R8, X and Z are as defined herein, and forms and compositions thereof.La présente invention concerne l'utilisation de composés 2-pyridinone polycycliques et de formes desdits composés pour traiter ou faire régresser les infections à Neisseria gonorrhoeae.
