Gianni Chessari,Maria Grazia Carr,Miles Stuart Congreve,Robert Downham,Martyn Frederickson,Christopher William Murray,Eva Figueroa Navarro,Michael Alistair OBrien,Theresa Rachel Phillips,Andrew James
申请号：
US12782996
公开号：
US08106057B2
申请日:
2010.05.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention provides methods for treating cancer, particularly hematopoietic tumors of lymphoid or myeloid lineage, prostate cancer, lung cancer, gastrointestinal stromal tumor, breast cancer and melanoma, which comprise administering to the mammal a compound, salt, hydrate, tautomer or N-oxide according to formula (I):and in particular, those of subgenus VIIaThese compounds inhibit or modulate the activity of the heat shock protein Hsp90.
