KARKI, SHYAM B.,ZAWANEH, PETER,LEUNG, CHEUK-YUI,VASUDEVAN, KALYAN,LIN, YIQING,XU, JIN,TREMENTOZZI, ANDREA
申请号：
CA2967647
公开号：
CA2967647A1
申请日:
2015.11.19
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention provides novel pharmaceutical compositions of dimethyl fumarate. The pharmaceutical compositions of the present invention are in the form of a bead and comprise (i) an inert core； (ii) a first layer surrounding the inert core, wherein the first layer comprises dimethyl fumarate； and (iii) an enteric coating surrounding the first layer. Also provided are pharmaceutical compositions in the form of a bead comprising a core and an enteric coating surrounding the core, wherein the core comprises dimethyl fumarate. Methods of using the pharmaceutical compositions of the present invention for treating multiple sclerosis are also included.
