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COMPOSITION PARTICULAIRE CONTENANT DE L'ACIDE ASCORBIQUE 2-O-ALPHA -D-GLUCOSYL-L CRISTALLIN ANHYDRE.
专利权人:
Hayashibara Co.; Ltd.
发明人:
申请号:
EP16166796.9
公开号:
EP3081573B1
申请日:
2010.09.03
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention aims to provide a particulate composition containing anhydrous crystalline 2-O- ± -D-glucosyl-L-ascorbic acid having a significantly, hardly solidifiable property compared to conventional ones in a grade for use in quasi-drugs; a process for producing the same; and uses thereof. The present invention solves the above object by providing a particulate composition containing anhydrous crystalline 2-O- ± -D-glucosyl-L-ascorbic in an amount of over 98.0% by weight but less than 99.9% by weight, on a dry solid basis; or a degree of crystallinity of 90% or higher for anhydrous crystalline 2-O- ± -D-glucosyl-L-ascorbic acid, when calculated based on a profile of powder X-ray diffraction analysis of the particulate composition, and a dynamic vapor sorption level of 0.01% by weight or lower, when kept at 25°C under a relative humidity of 35% by weight for 12 hours after removal water in the particulate composition under nitrogen gas stream; and by providing a process for producing the same and uses thereof.
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中国工程科技知识中心
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