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Imidazopyridin-2-one derivatives
专利权人:
DAIICHI SANKYO COMPANY; LIMITED
发明人:
OHTSUKA, MASAMI,HAGINOYA, NORIYASU,ICHIKAWA, MASANORI,MATSUNAGA, HIRONORI,SAITO, HIRONAO,SHIBATA, YOSHIHIRO,TSUNEMI, TOMOYUKI
申请号:
ES09804973
公开号:
ES2459047T3
申请日:
2009.08.04
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
A compound represented by the general formula (I): ** Formula ** 5 in which in the general formula (I), (R1) nA- is a 1H-pyrrolo [2,3-b] pyridin-5- group ilo, a 3-chloro-1H-pyrrolo [2,3-b] pyridin-5-yl group, a 4-chloro-1Hpyrrolo [2,3-b] pyridin-5-yl group, a 3-fluoro- group 1H-pyrrolo [2,3-b] pyridin-5-yl, a 4-fluoro-1H-pyrrolo [2,3-b] pyridin-5-yl group, a 3-methyl-1H-pyrrolo [2, 3-b] pyridin-5-yl, a 4-methyl-1H-pyrrolo [2,3-b] pyridin-5-yl group, a 3,4-dimethyl-1H-pyrrolo [2,3-b] group pyridin-5-yl, a 3-fluoro-4-methyl-1H-pyrrolo [2,3-b] pyridin-5-yl group or a 3-chloro-4-methyl-1H10 pyrrolo [2,3-b group ] pyridin-5-yl, B is a 3 to 7-membered saturated or partially saturated monocyclic hydrocarbon group and may contain 1 or 2 oxygen atoms, sulfur atoms, nitrogen atoms, sulfinyl groups and / or sulfonyl groups as constituents of ring, B may have the same or different m R2s as substituents, R2 is a substituent present on a carbon atom or á nitrogen atom that forms B, R2 is a substituent selected from the group consisting of a hydroxy group, a halogen atom, a cyano group, an oxo group, a C1-4 alkyl group (in which the C1-4 alkyl group it may be substituted with 1 or 2 C1-4 alkoxy groups), a C1-4 alkoxy group, a halogen-C1-4 alkyl group, a C1-4 alkyl sulfonyl group, a C1-4 alkylcarbonyl group and - NR10aR10b when R2 is a substituent present in a carbon atom that forms B, and R2 is a substituent selected from the group consisting of a hydroxy group, a C1-4 alkyl group (in which the C1-4 alkyl group may be substituted with 1 or 2 C1-4 alkoxy groups), a C1-4 alkoxy group, a halogen-C1-4 alkyl group, a C1-4 alkyl sulfonyl group, a C1-4 alkylcarbonyl group and -NR10aR10b when R2 is a substituent present in a nitrogen atom that forms B, R10a and R10b are the same or different and are each a hydrogen atom or a C1-4 alkyl group, m is any number Ero integer from 0 to 3, Q is a bond or a C1-4 alkylene group, R3 and R4 are the same or different and are each a hydrogen atom, a h
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