Described are syringe devices useful in delivering medical materials internally in patients. In certain embodiments, syringe devices of the invention include widening internal lumen to assist in effective delivery of substances therethrough, and/or curved barrel portions with curved lumens therein. In still further disclosed embodiments, syringe devices include adaptations to prevent compression of compressible carrier materials to be delivered therethrough, curved barrel portions with flexible plunger arms to track the curved barrel portions, barrel portions controllable in shape such as to introduce and remove curves, visible markings to denote the direction of deflection of syringe barrel portions, imagable markers located on the syringe barrel, a cooperating plunger apparatus, or both or combinations of some or all of these features. Further described are spinal fusion procedures with syringe-based delivery of osteogenic material through a minimally invasive procedure, which procedures can utilize syringe devices of the invention.
