The present invention relates to specific indolinone derivatives, namely the compounds of formulain which R1represents an hydrogen atom or a Cl-CH2-CO-group, and R2and R3each represent an hydrogen atom or R2and R3taken together represent agroup, with the proviso that when R1represents an hydrogen atom R2and R3taken together represent agroup, and to a process for their manufacture.本發明係關於特定吲哚啉酮衍生物,亦即下式化合物其中R1表示氫原子或Cl-CH2-CO-基團,且R2及R3各自表示氫原子或R2與R3一起表示基團,其限制條件為當R1表示氫原子時,R2與R3一起表示基團,及其製備方法。