Itu, Lucian Mihai,Sharma, Puneet,Redel, Thomas,Georgescu, Bogdan
申请号：
ES15166816
公开号：
ES2641688T3
申请日:
2015.05.07
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A computer-implemented method for hemodynamic assessment of a coronary artery (208, 208) based on data of medical images of a patient comprising: extracting (104) the specific anatomic measurements of the coronary arteries (206, 208) patient data from medical images of a patient； calculating (106) the specific boundary conditions of the patient of a computerized model of coronary circulation representing the coronary arteries (206, 208) based on anatomical measurements of specific coronary arteries (206, 208) of the patient； simulating (108) the flow and blood pressure in the coronary arteries (206, 208) using the computerized model of the coronary circulation and the specific boundary conditions of the patient, and model (108) coronary autoregulation during flow simulation and the blood pressure in the coronary arteries (206, 208)； and calculating (112) a hemodynamic index for at least one region of the coronary arteries (208, 208) based on the blood flow and the simulated pressure； characterized in that model (108) coronary autoregulation during simulation of blood flow and pressure in the coronary arteries (206, 208), comprising: for each coronary artery stenosis (212, 214) on the computer model of coronary circulation adapt microvascular resistance at the outputs of the computerized model of the coronary circulation stream down the coronary artery stenosis (212, 214) based on a fall in the simulated pressure on the coronary artery stenosis (212, 214) and a simulated flow through the coronary artery stenosis (212, 214) and for each of a plurality of branches in a coronary arterial tree (500) of the patient in the computer model of coronary circulation: if a current branch includes a region of stenosis (212 , 214) calculate an adjusted resistance current branch by subtracting a resistance of the region of stenosis (212, 214) estimates It gives based on the pressure values and simulated flow from a microvascular equivalent resistance of the current branch； and mo
