The present invention relates to epitope peptides (or mutants thereof) for treating hepatitis B virus infection recombinant proteins comprising such epitope peptides (or mutants thereof) and carrier proteins and uses of such epitope peptides (or mutants thereof) and recombinant proteins. The present invention also relates to antibodies against such epitope peptides cell lines producing said antibodies and uses thereof. Furthermore the present invention relates to vaccines or pharmaceutical compositions for treating or alleviating one or more symptoms relating to hepatitis B virus infection which respectively comprise recombinant proteins or antibodies in the present invention.