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Modifisert Vaccinia Ankara virusstamme MVA-BN og derivater derav, fremgangsmåter for introduksjon av nukleinsyresekvens i målceller, fremstilling av peptid eller protein og fremstilling av variant av MVA, celle som inneholder varianten, sett for immunisering samt anvendelse av varianten.
专利权人:
Bavarian Nordic A/S
发明人:
Chaplin, Paul,Howley, Paul,Meisinger, Christine
申请号:
NO20032309
公开号:
NO337867B1
申请日:
2003.05.21
申请国别(地区):
NO
年份:
2016
代理人:
摘要:
The present invention provides an attenuated virus, which is derived from Modified Vaccinia Ankara virus and which is characterized by the loss of its capability to reproductively replicate in human cell lines. It further describes recombinant viruses derived from this virus and the use of the virus or its recombinants as medicament or vaccine. Additionally, a method for inducing an immune response even in immuno-compromised patients, patients with pre-existing immunity to the vaccine virus or patients undergoing antiviral therapies is provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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