An occluder for the left atrial appendage is disclosed which includes a radially self-expandable radially radially self-expandable thread braid including a braid so as to be in an expanded state substantially perpendicular to the inner wall surface of the left atrial appendage Whereby the braid is engageable with the inner wall of the proximal end of the left atrial appendage, and in the expanded state, the proximal portion is deformable by the inner wall and is attached to the inner wall Said braid having rigidity and elasticity defined to coincide, said braid having, after expansion in said radial direction, along the sealing of said braid extending longitudinally of said occluder, substantially perpendicular to said radial direction To form a sealed connection with the inner wall. The occluder further includes a distal anchor portion, the distal anchor portion including a fixation wire radially expandable from a reduced diameter shape to an expanded diameter shape, the anchor portion being defined larger than the proximal portion And the occluder includes a bending element that connects the anchoring portion and the proximal portion and is configured such that the anchoring portion and the proximal portion from the relaxed configuration to the deployed configuration As shown in FIG.(Fig. 6a).左心耳用のオクルーダーが開示され、該オクルーダーは、左心耳の内壁の表面にほぼ垂直な拡張状態になるように径方向で放射状に自己拡張自在な少なくとも1本の糸の組みひもを含む近位部を含み、それにより、前記組みひもは、前記左心耳の近位端の前記内壁と係合自在となり、前記拡張状態において、前記近位部は、前記内壁により変形自在であり且つ前記内壁に一致するよう画定された剛性及び弾性を有し、前記組みひもは、前記径方向での拡張後に、前記径方向にほぼ垂直な、前記オクルーダーの長手方向に延びる前記組みひもの密封部に沿って前記内壁との密封接続を形成するように構成される。前記オクルーダーは更に、遠位固着部を含み、該遠位固着部は、小径形状から拡径形状へと放射状に拡張自在な固着ワイヤを含み、前記固着部は前記近位部よりも大きな画定された剛性を持ち、及び、前記オクルーダーは屈曲要素を含み、該屈曲要素は、前記固着部と前記近位部を接続し、且つ、緩和形態から展開形態への前記固着部と前記近位部との間の移動を可能にする。【選択図】図6a
