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A P53 mutánsok újraaktíválására képes peptidek
专利权人:
Yeda Research and Development Co. Ltd
发明人:
OREN, Moshe,ROTTER, Varda,Tal, Perry
申请号:
HUE14834903
公开号:
HUE049292T2
申请日:
2014.08.07
申请国别(地区):
HU
年份:
2020
代理人:
摘要:
The invention provides peptides that can reactivate p53 mutants efficiently and specifically, as well as methods that allow the identification, selection and isolation of such peptides, in a precise, cost and time effective manner. In particular, there are provided mutant p53 reactivating peptides that can restore the native wild type p53 folding, and hence the tumor suppressor activity, to the mutant p53 protein. Such peptides are useful for treating various conditions and diseases in which p53 is mutated.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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