COMPOSÉS ET COMPOSITIONS SERVANT DE MODULATEURS DE L' ACTIVITÉ DES TLR

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专利权人:

NOVARTIS AG

发明人:

申请号：

EP09718298.4

公开号：

EP2268618B1

申请日:

2009.02.27

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N； X4 is N Or CR3； X5 is -CR4=CR5.

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中国工程科技知识中心

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