Institut Pasteur de Lille;Institut National de la Santé et de la Recherche Médicale (INSERM)
发明人:
Luis Solans,Camille Locht,Anne Tsicopoulos,Saliha Ait-Yahia Sendid
申请号：
US16863972
公开号：
US20200323901A1
申请日:
2020.04.30
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method of reducing or preventing the development of airway inflammation in a subject includes the step of infecting the respiratory tract of a subject an amount of a composition including a pharmaceutically acceptable carrier and live attenuated pertactin-deficient Bordetella bacteria sufficient to colonize the respiratory tract of the subject. The step of infecting the subject with the live attenuated pertactin-deficient Bordetella bacteria results in reduction or prevention of the development of airway inflammation in the subject.
