The invention relates to a self-foaming composition containing brimonidine, for a no-rinse topical application, comprising: at least one intermediate composition B comprising a gas-generating agent； at least one intermediate composition A comprising an agent for activating the gas-generating agent； and brimonidine or one of the pharmaceutically acceptable salts thereof contained in at least one of said intermediate compositions A and B. The invention also relates to a kit or a single container comprising a plurality of compartments containing such a composition.
