An inhalable composition for use as a medicament in the treatment of a subject, wherein said composition comprises: (i) one or more cannabinoids or pharmaceutically acceptable derivative or salt thereof； (ii) a propellant； (iii) a monohydric or polyhydric alcohol and(iv) a glycol and/or glycol ether, characterised in that the ratio of monohydric or polyhydric alcohol to glycol or glycol ether by weight is from 6:1 to 1:1, wherein the composition is administered in the form of an aerosol having a fine particle fraction (FPF) of 60% or more. Also disclosed is a method of manufacturing the above composition, and a pressurised container therefor. The inhaler may comprise a housing, a reservoir within the housing containing the inhalable composition comprising a cannabinoid and an alcohol, a composition flow path from the reservoir and an outlet at an inhaling end of the housing, and a non-metered breath operated outlet valve for controlling the flow of inhalable composition through the flow path.
