An incontinence treatment device includes a synthetic urethra and a cuff separate from the synthetic urethra. The synthetic urethra provides a flow diameter that is configured to be spliced into a natural urethra such that the flow diameter is aligned with a lumen of the natural urethra for passage of urine. A closure device includes a pump communicating between a reservoir and the cuff. The cuff is attachable around an outer circumference of the synthetic urethra. The pump is operable to move a liquid from the reservoir to inflate the cuff, the inflated cuff adapted to circumferentially compress and constrict the flow diameter of the synthetic urethra.