The present invention relates to an artificial nephron device. The artificial nephron device comprising a multi micro channel in which while blood containing waste and water are passing therethrough the waste is separated so as to purify the blood and the separated waste is concentrated into the water to be discharged, wherein the multi micro channel comprises a glomerulus micro channel simulating a Glomerulus, a tubule micro channel simulating a Tubule, and a Henles loop micro channel simulating a Henles loop. According to the present invention, the device can be made smaller and can be optimized, and an artificial kidney of high efficiency can be made by the series or parallel combination of the devices, so the demand for a portable artificial kidney and the domiciliary hemodialysis system can be increased and life quality of patients suffering from chronic renal insufficiency can be improved.
