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GPR119 AGONISTS
专利权人:
ELI LILLY AND COMPANY
发明人:
BUENO MELENDO, ANA, BELEN,FRANCISKOVICH, JEFFRY, BERNARD,BARRETT, DAVID, GENE,LIU, BIN,TAKEUCHI, KUMIKO
申请号:
NZ59712510
公开号:
NZ597125A
申请日:
2010.07.12
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
Disclosed herein are compounds of formula (I), wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as G protein-coupled receptor 119 (GPR119) agonist and as such is useful in the treatment of diabetes or obesity. Specifically preferred compounds include: 5-[1-(2-fluoro-2-methyl-propyl)-piperidin-4-ylmethoxy]-1'methanesulfonyl-1',2',3 ',6'-tetrahydro-[2,4']bipyridinyl; 1-methanesulfonyl-4-{ 4-[ 1-(1-trifluoromethyl-cyclopropylmethyl)-piperidin-4-ylmethoxy ]-phenyl} -1,2,3,6-tetrahydro-pyridine.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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