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Stabilized radiopharmaceutical composition, method for preparing it, and use of gentisic acid or a salt thereof with a biocompatible cation.
专利权人:
GE HEALTHCARE BV
发明人:
JAN VAN DEN BOS
申请号:
BRPI0820438
公开号:
BRPI0820438A2
申请日:
2008.11.04
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention relates to stabilised radiopharmaceutical compositions which comprise: (i) an 18F-labelled compound; (ii) an effective stabilizing amount of gentisic acid or a salt thereof with a biocompatible cation; (iii) an aqueous biocompatible carrier medium; wherein the radioactive concentration of the 18F in the carrier medium is in the range 10 to 100,000 MBq/ml and the pH of the composition is in the range 4.0 to 9.5. The invention further comprises methods for preparing such radiopharmaceutical compositions and a new use of gentisic acid or a salt thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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