Robinson, Simon P.,Harris, Thomas D.,Yu, Ming,Radeke, Heike S.,Purohit, Ajay,Casebier, David S.,Azure, Michael T.
申请号:
AU2007339954
公开号:
AU2007339954B2
申请日:
2007.12.21
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit increased stability, decreased NE release (thereby reducing side effects), improved quantitative data, and/or high affinity for VMAT over prior radiotracers. Methods of using the compounds to image cardiac innervation are also provided. In some instances the compounds are developed by derivatizing certain compounds with