#$%^&*AU2011250875B220120906.pdf#####ABSTRACT An embodiment relates to a method for delivering a unidirectional afferent nerve stimulation treatment. A test neural stimulation is delivered, and a physiologic response to the test neural stimulation is monitored. At least one neural stimulation parameter for the test neural stimulation is adjusted if the test neural stimulation does not elicit a desired physiologic response. If the test neural stimulation does elicit the desired physiologic response, at least one treatment parameter for a unidirectional afferent nerve stimulation is determined using the at least one neural stimulation parameter for the test neural stimulation that provided the desired physiologic response. The unidirectional afferent nerve stimulation is delivered using the at least one treatment parameter. 1558005_i.doc4/11 SDELIVER TEST NEURAL STIMULA TION (E.G. EFFERENT TO ELICIT PHYSIOLOGIC RESPONSE ESIE ADJUST TEST PHYSIOLOGIC NS PARAM EER SRSONE RESPONSE? DETERMINE TREATMENT PARAMETERS FOR UNIDIRECTIONAL AFFERENT STIMULATION USING TEST NS PARAMETERS DELIVER UNIDIRECTIONAL AFFERENT STIMULATION USING TREATMENT PARAMETERS FIG.5 DELIVER TEST EFFERENT STIMULATION USING TRIPOLAR CUFF ELECTRODE, -+USING TEST PARAMETER SET C FOR CATHODE ELECTRODE, TEST PARAMETER SET Al FOR FIRST ANODE, AND TEST PARAMETER SET A2 FOR SECOND ANODE ADJUST PARAMETER(S) ESIRE FOR AT LEAST ONE OF TEST :PHYSIOLOGIC PARAMETER SETS C, A 1, A2 RESPONSE? DETERMINE TREATMENT PARAMETER SETS C, A 1, A2 FOR UNIDIRECOIlNAL AFERENTSMULATION USING TEST PARAMETER SETS C, Al, A2 DELIVER UNIDIRECTIONAL AFFERENT STIMULATION USING TEST PARAMETER SETS C, AI A2 FIG. 6