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Salts of 4-aniline quinazoline derivative
专利权人:
Jianhui Guo
发明人:
Jianhui Guo,Yong Jiang
申请号:
US12527345
公开号:
US08349854B2
申请日:
2008.02.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to salt forms of N-{4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]-quinazolin-6-yl}-acrylamide as exemplified by formula (I), methods of preparation thereof, pharmaceutical compositions comprising the same and their use thereof. The salt forms of the present invention, which possess excellent tumor inhibitory activity, good bioavailability and low toxicity in an animal body, are suitable for use of preparation of anti-tumor medicaments.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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