Michel Streuli,Venkataraman Sriram,Aritra Pal,Leonard G. Presta
申请号:
US16601233
公开号:
US20200140546A1
申请日:
2019.10.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are anti-TREM2 antibodies and related methods of making and using anti-TREM2 antibodies. Also provided are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an anti-TREM2 antibody or antigen binding fragment thereof.