Hans-Georg Lerchen,Sherif El Sheikh,Beatrix Srelte Ludwig,Sven Golfier,Joachim Schumacher,Joan Mark Gnoth,Ursula Krenz
申请号：
US13876777
公开号：
US20130261064A1
申请日:
2011.09.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present application relates to new derivatives of monomethylauristatin F, substituted on the N terminus by a carboxyalkyl group, processes for preparing these derivatives, their use for the treatment and/or prevention of diseases and to produce medication for the treatment and/or prevention of diseases, particularly hyperproliferative and/or angiogenic disorders such as cancer disorders, for example. Such treatments can occur as monotherapies or in combination with other medication or further therapeutic measures.
