Hnisz Denes,Abraham Brian,Lee Tong Ihn,Young Richard A.
申请号:
US201514873962
公开号:
US10160977(B2)
申请日:
2015.10.02
申请国别(地区):
美国
年份:
2018
代理人:
Warren, Esq. Lisa M.`Morse, Barnes-Brown & Pendleton, P.C.
摘要:
The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).