Baettig, Urs,Bala, Kamlesh Jagdis,Budd, Emma,Edward, Lee,Howsham, Catherine,Hughes, Glyn,Legrand, Darren Mark,Spiegel, Katrin
申请号：
ES14191369
公开号：
ES2623848T3
申请日:
2011.03.17
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
Compound for use in the treatment of chronic obstructive pulmonary disease selected from: ((S) -3,3,3-trifluoro-2-hydroxy-2-methyl-propyl) -amide of 3-amino-6-methoxy-acid 5-trifluoro-methyl-pyridine-2-carboxylic acid； 3-Amino-6-methoxy-5-trifluoro-methyl-pyridine-2-carboxylic acid ((R) -3,3,3-trifluoro-2-hydroxy-2-methyl-propyl) -amide； 3-Amino-6- (4-fluoro-phenyl) -5-trifluoro-methyl-pyridine-2-carboxylic acid (3,3,3-trifluoro-2-hydroxy-2-methyl-propyl) -amide； 3-Amino-5,6-bis-trifluoro-methyl-pyridine-2-carboxylic acid ((S) -3,3,3-trifluoro-2-hydroxy-2-methyl-propyl) -amide and ((R 3-Amino-5,6-bis-trifluoro-methyl-pyridine-2-carboxylic acid -3,3,3-trifluoro-2-hydroxy-2-methyl-propyl) -amide； or a pharmaceutically acceptable salt thereof.Compuesto para su uso en el tratamiento de enfermedad pulmonar obstructiva crónica seleccionado de: ((S)-3,3,3-trifluoro-2-hidroxi-2-metil-propil)-amida del ácido 3-amino-6-metoxi-5-trifluoro-metil-piridin-2-carboxílico； ((R)-3,3,3-trifluoro-2-hidroxi-2-metil-propil)-amida del ácido 3-amino-6-metoxi-5-trifluoro-metil-piridin-2-carboxílico； (3,3,3-trifluoro-2-hidroxi-2-metil-propil)-amida del ácido 3-amino-6-(4-fluoro-fenil)-5-trifluoro-metil-piridin-2-carboxílico； ((S)-3,3,3-trifluoro-2-hidroxi-2-metil-propil)-amida del ácido 3-amino-5,6-bis-trifluoro-metil-piridin-2-carboxílico y ((R)-3,3,3-trifluoro-2-hidroxi-2-metil-propil)-amida del ácido 3-amino-5,6-bis-trifluoro-metil-piridin-2-carboxílico； o una sal farmacéuticamente aceptable del mismo.
