N-SUBSTITUTED BENZENEPROPANAMIDE OR BENZENEPROPENAMIDE FOR USE IN THE TREATMENT OF PAIN AND INFLAMMATION

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专利权人:

发明人:

申请号：

EP10759717.1

公开号：

EP2475361A1

申请日:

2010.09.09

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Compounds for use in the treatment or prophylaxis of pain, including acute and chronic pain (e.g., nociceptive pain, neuropathic pain, headaches, migraine), represented by general formula (I), in which: the dotted line represents a single or a double bond and R5 and R5 are independently -H, -OH or -OR6, where R6 is a linear or branched C1-C4 alkyl X is -CH2O-, Z is -CH2CH2O-CH(CH3)CH2O- or -CH2CH(CH3)O- m is 1 and n is an integer of 1- 5. The compounds of the invention are also effective for reducing inflammation and may be used alone or in combination with other analgesics.

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