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CYCLIC AMIDE DERIVATIVE
专利权人:
发明人:
Akihiro OKANO,Munetaka OHKOUCHI,Muneyoshi MAKABE
申请号:
US14729979
公开号:
US20150266839A1
申请日:
2015.06.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
[Problem]To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogues and a prophylactic and/or therapeutic agent against diabetes, obesity, or the like.[Means of Solving the Problem]A compound of Formula (III):(where f is 0 to 2 g is 1 to 4 j is 0 to 3 k is 0 to 2 n is 0 to 2 p is 0 to 4 his 0 to 3 q1 id 0 to 3 q2 is 0 or 1 r1 is 0 to 2 (with the proviso that q1+q2+r1 is 0 to 5) J1a is —CR11a—, N J2 is —CR12aR12b—, —CR12c— T is —CH2—, O, —S(O)i— (i is an integer of 0 to 2) or —NR7— X is O, S, or —NR7— ring A′″ is a benzene ring, a pyridine ring ring B′ is a benzene ring, a pyridine ring, a pyrimidine ring and R1 to R14 are specific groups), a salt of the compound, or a solvate of the salt or the compound.
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