The present invention relates to a pharmaceutical composition for use in the treatment of a disease or condition, wherein said disease or condition is associated with stenosis or/and obstruction located in the pancreatic duct system, said composition comprising at least one GLP-1 agonist and optionally a pharmaceutically acceptable carrier, diluent or/and auxiliary substance.本發明是有關於一種用於治療疾病或症狀的醫藥組成物,其中該疾病或症狀與位在胰管系統中的狹窄或/及阻塞有關,該組成物包含至少一種GLP-1促進劑以及視情況選用之醫藥上可接受載劑、稀釋劑或/及輔劑。