Systems and methods for adaptive sensors calibration are provided. The traditional systems and methods provide for heart rate monitoring using PPG methods but do not focus on adaptive calibration with real-time feedback and dynamic signal quality validation. Embodiments of the present disclosure provide for obtaining an initial value pertaining to a set of calibration parameters of a first sensor and performing a comparison with a pre-defined threshold； incrementing value of the set of calibration parameters by a pre-defined value and performing a comparison； obtaining from the sensor configuration matrix, an initial value pertaining to a set of calibration parameters of a second sensor and performing a comparison； and repeating the steps performed above if the comparisons performed does not match pre-defined quality threshold and finally updating sensor configuration matrix whenever pre-defined quality threshold is matched.
