SYSTEMES, COMPOSITIONS, ET PROCEDES DE DECOUVERTE DE MSI ET DE NEOEPITOPES QUI PREVOIENT LA SENSIBILITE A DES POINTS DE CONTROLE IMMUNITAIRES

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专利权人:

NANTOMICS; LLC

发明人:

NGUYEN, ANDREW,NIAZI, KAYVAN,SOON-SHIONG, PATRICK,BENZ, STEPHEN CHARLES,RABIZADEH, SHAHROOZ

申请号：

CA3003251

公开号：

CA3003251A1

申请日:

2016.10.12

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Systems and methods are presented that allow for predicting treatment response of a tumor to a checkpoint inhibitor. In one exemplary aspect, the treatment response is directly associated with a relatively high number of patient- and tumor-specific immunologically visible neoepitopes. Specific mutational patterns in the nucleic acid encoding the neoepitope may be further indicative of treatment response.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/