NGUYEN, ANDREW,NIAZI, KAYVAN,SOON-SHIONG, PATRICK,BENZ, STEPHEN CHARLES,RABIZADEH, SHAHROOZ
申请号：
CA3003251
公开号：
CA3003251A1
申请日:
2016.10.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Systems and methods are presented that allow for predicting treatment response of a tumor to a checkpoint inhibitor. In one exemplary aspect, the treatment response is directly associated with a relatively high number of patient- and tumor-specific immunologically visible neoepitopes. Specific mutational patterns in the nucleic acid encoding the neoepitope may be further indicative of treatment response.
