<;P>;PROBLEM TO BE SOLVED: To provide a polymer base material which has high safety and high blood group compatibility and to which a saccharide having great ability to adsorb/remove a botulinum toxin is bonded and to provide a method for producing the polymer base material, and a medical appliance using the polymer base material. <;P>;SOLUTION: The polymer base material is produced by bonding a saccharide-bonded polymer chain to a polymer support such as a hollow fiber membrane having a methylene group in one molecule thereof by a graft polymerization reaction. The medical appliance using the fixed polymer base material is also provided. <;P>;COPYRIGHT: (C)2011,JPO&INPIT