Activation CD89 dans une thérapie

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专利权人:

CSL Behring AG;Universität Bern

发明人:

申请号：

EP10194942.8

公开号：

EP2465536A1

申请日:

2010.12.14

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.

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