A venipuncture device may be used for assisting a healthcare provider identify and locate a blood vessel in a patient. According to embodiments, heat is applied to a selected venipuncture site on the patents limb. A pressure cuff constricts the limb proximal to the venipuncture site, thereby partially occluding blood flow through the blood vessel and engorging the blood vessel and making it more visible to the healthcare provider. The healthcare provider may then carry out various operations on the patient, including but not limited to drawing blood and insertion of an intravenous line.