GENOME EDITING IN RATS USING ZINC-FINGER NUCLEASES

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专利权人:

SANGAMO BIOSCIENCES; INC.

发明人:

CUI, XIAOXIA,GEURTS, ARON M.,URNOV, FYODOR

申请号：

EP09830727

公开号：

EP2352369A4

申请日:

2009.12.03

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Disclosed herein are methods and compositions for genome editing of one or more loci in a rat, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.

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中国工程科技知识中心

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http://www.ckcest.cn/home/