Maria KAVALLARIS,Pei Pei GAN,Joshua Adam MCCARROLL
申请号：
US14951992
公开号：
US20160175339A1
申请日:
2015.11.25
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided herein is a method of screening a tumour cell for resistance to a tubulin-binding agent, the method comprising detecting the expression of any one or more of class II, class III and class IVb β-tubulin by the tumour cell, wherein the expression of any one or more of class II, class III and class IVb β-tubulin indicates that the tumour cell has resistance or potential resistance to the tubulin-binding agent. Also provided are methods of modulating the sensitivity of a tumour cell Also provided is a method of modulating the tumorigenesis of a tumour cell.
