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Anti-RSV immunogens and methods of immunization
专利权人:
Department of the Health and Human Services; Centers for Disease Control and Prevention; as represented by the Secretary;The Government of the United States of America
发明人:
Anderson, Larry J.,Haynes, Lia M.,Tripp, Ralph A.
申请号:
AU2010279492
公开号:
AU2010279492A1
申请日:
2010.08.04
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Immunogenic polypeptides corresponding to one or more RSV G glycoproteins, or analogues thereof, are provided as components of vaccines. The inventive compositions are useful as both a prophylactic and therapeutic for the prevention and treatment of RSV infections and associated pulmonary or other diseases. The inventive immunogens include regions of the RSV G protein, specifically, amino acid residues 164-176 of RSV G A2 protein or analogues thereof. This inventive immunogen is operable alone or in combination with other polypeptides such as the RSV G protein amino acid residues 155-206, or other vaccines such as live RSV vaccines, or inactivated RSV vaccines or immunogenic analogues thereof.
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