Joon Jung,Thomas Wai-Ho Lee,Rajesh R. Iyengar,Nicholas Robert Perl,Peter Germano,Maria D. Ribadeneira,Kim Tang
申请号：
US16348359
公开号：
US20190343813A1
申请日:
2017.11.07
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3′；,5′；-monophosphate (cGMP) or both, or an upregulation of the NO pathway is desirable.
