Gretchen Schroeder;Ashok V. Purandare;Jennifer Inghrim;Honghe Wan;James W. Grebinski;Amy Hart
发明人:
Ashok V. Purandare,James W. Grebinski,Amy Hart,Jennifer Inghrim,Gretchen Schroeder,Honghe Wan
申请号:
US12874276
公开号:
US08202881B2
申请日:
2010.09.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds of formula Iand pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.