寡聚物及寡聚物結合物农业专利-农业学术服务平台

发明人:: JAVANBAKHT, HASSAN,杰凡巴克特　海珊,傑凡巴克特　海珊,OTTOSEN, SOREN,欧特森　索伦,歐特森　索倫,LINDOW, MORTEN,林都　摩顿,林都　摩頓,杰凡巴克特海珊,傑凡巴克特海珊,欧特森索伦,歐特森索倫,林都摩顿,林都摩頓

摘要：: The present invention relates to an oligomer conjugate for use in the treatment of a viral disorder. The oligomer conjugate comprises: a) an oligomer capable of modulating a target sequence in HBx and/or HBsAg of Hepatitis B Virus (HBV) to treat said viral disorder； and b) a carrier component capable of delivering the oligomer to the liver which is linked, preferably conjugated, to the oligomer.本發明係關於用於治療病毒病症之寡聚物結合物。該寡聚物結合物包含：a)能夠調節B型肝炎病毒(HBV)之HBx及/或HBsAg中之靶序列以治療該病毒病症之寡聚物；及b)能夠將該寡聚物遞送至肝之載劑組份，其連接、較佳結合至該寡聚物。