KHANDKE LAKSHMI,CHEN YING,HAN HANYOUNG,SEID ROBERT CHANCEY JR.,JIN ZHAOWEI,LOOK JEE LOON,MALONE RONALD,YANG XUDONG,KHANDKE Lakshmi,CHEN Ying,HAN Hanyoung,SEID Robert Chancey Jr.,JIN Zhaowei,LOOK Jee Loon,MALONE R
申请号：
SI200731706
公开号：
SI2010219T1
申请日:
2007.04.19
申请国别(地区):
SI
年份:
2015
代理人:
摘要：
The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like.
