JOEL TOCKER,JACQUES J. PESCHON,DAVID FITZPATRICK,CHING LIM AI,CHRISTOPHER MEHLIN,JAMES F. SMOTHERS
申请号：
PT12159118
公开号：
PT2518085T
申请日:
2007.10.01
申请国别(地区):
PT
年份:
2017
代理人:
摘要：
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
