PROBLEM TO BE SOLVED: To provide a noninvasive administration drug delivery system having excellent drug migration properties to the posterior part tissue of the eye through the local part tissue of the eye.SOLUTION: The drug delivery system having the excellent drug migration properties to the posterior part tissue of the eye through the local part tissue of the eye is constructed by administering the solid composition comprising a medicine and a mucous membrane-adhesive material having 200-1,000 g adhesivity to the interior of the conjunctival sac.COPYRIGHT: (C)2007,JPO&INPIT【課題】眼局所組織を介した後眼部組織への薬物移行性が優れた非侵襲性投与ドラッグデリバリーシステムを開発すること。【解決手段】薬物と付着力が200~1000gの粘膜付着性物質からなる固形組成物を結膜嚢内へ投与することにより、眼局所組織を介した後眼部組織への薬物移行性が優れたドラッグデリバリーシステムを構築できる。